Skip to main content
  1. Home
  2. Travel
  3. Features

How to Spend 36 Hours in Santiago, Chile

Whether you are traveling to South America and have a layover that can be extended in Santiago or you are just visiting the capital of Chile, there are a few things you just can’t miss in this lovely city. From specific neighborhoods to restaurant options to must-see tourist attractions, our guide is meant to provide you with some solid options as well as inspire you to spend some time in Santiago.

santiago chile
SWL Fotografía/Getty Images

Saturated with colonial architecture blended with steel skyscrapers —  like the Gran Torre Santiago, Latin America’s tallest building — Santiago sits in a valley of the Andes Mountains surrounded by snow-capped peaks. Home to approximately 5.6 million, a third of the entire country’s population, Santiago’s diversity is clearly distinguished with the different barrios (neighborhoods) located within the capital city.

Recommended Videos

Author’s note: International news media has currently been exaggerating the extent of the dangers of visiting Santiago due to organized peaceful protests that have been taking place weekly. From what I personally witnessed while there, the only danger that may come to tourists who are visiting is if they happen to go near the organized protests. The police have been authorized to use force, including rubber bullets, to disperse crowds, which has resulted in many serious and permanent injuries. It’s recommended that you avoid areas where locals are protesting or marching. But to be clear, there are no violent riots taking place.

Santiago Neighborhoods to Explore

Bellavista: This bohemian neighborhood is decorated with vibrant street art and is known for its late-night scene. The streets are lined with bars, clubs, and great places to eat. Also important to note, the neighborhood provides direct access to Cerro San Cristobal through Santiago’s Metropolitan Park and offers one of the best views in the city.

bellavista
Diegograndi/Getty Images

Parque Bustamante: Located between the center of the city and the rest of the province, Parque Bustamante is chock full of bold architecture that surrounds many small parks. Come here to find cute coffee shops and inviting park benches that are perfect for people watching. The neighborhood is also home to Café Literario, a public library and café.

Barrio Italia: Located in the northern parts of the city, Barrio Italia is the true bohemian center of Santiago. Here you will find old Italian-influenced buildings and lots of tasty restaurants with international cuisine. Barrio Italia is home to many of the city’s youthful and artistic residents.

barrio italia
Matt Mawson/Getty Images

Bellas Artes and Lastarria: Both of these neighborhoods surround Museo Bellas Artes, which is why they combine to be a slightly more fashion-forward, artsy barrio. This is the place to come on the weekend when looking for books and antiques. In addition to access to this incredible art museum, Cerro Santa Lucio borders Lastarria from the center of Santiago and offers incredible views.

Centro Historico: The historical center of Santiago is home to Plaza de Armas, one of the main plazas in the city, the Cathedral of Santiago, and the National Historical Museum. Head here to learn about the history of Santiago as well as witness some of the many street performers that dominate the area.

santiago chile
Eleanor Scriven/Getty Images

Patronato: Located north of Bellavista, Patronato is the city’s cosmopolitan hub with a large international population. This neighborhood is best known for its diversity. The barrio is filled with unique shopping and eating experiences that are not typical of Santiago, so come here for something that is distinctly different from the rest.

What Not to Miss

Museo Chileno de Arte Precolombino: Santiago has many wonderful museums worth visiting but you should absolutely start with Museo Chileno de Arte Precolombino, which houses a massive collection of artifacts from many different cultures and ancestries of Central and South America. Here you will find various works of pottery and jewelry and most importantly, English translations to help ensure a smooth experience.

Museo Chileno Arte Precolombino
Museo Chileno Arte Precolombino

San Cristobal Hill: Since Santiago is located at a higher altitude, it might be best to save this activity until you’ve become acclimated to the difference in altitude. After a 45-minute moderate hike to the top of the hill, visitors will find the Chilean National Zoo, as well as 1,800 acres of park, including a Japanese garden. For those not looking to hike, you can also take a funicular ride to the top, which boasts more incredible views of the city.

La Chascona: One of the most internationally recognized Chileans of all time is famous poet and politician Pablo Neruda. All three of his homes have been transformed into museums for tourism, but it’s La Chascona, his home in Santiago, which garners the most attention. The home was built with multiple levels into the base of San Cristobal hill in Bellavista. Visitors can take a self-guided audio tour of the home where they can learn about not only the architecture but how it was nearly destroyed in 1973 after the military coup that overthrew Chile’s then-president.

Fundacionneruda/Getty Images

Where to Eat

Happening: Situated in the Las Condes neighborhood, the Happening Restaurant specializes in Argentine food, emphasizing meat-based dishes. The restaurant is equally recognized for the variety and quality of wines it offers. The servers here are happy to guide you when it comes to choosing the cooking point of the meats, as there is a wide selection from traditional wide steak to loin medallion to tenderloin steak.

El Ancla: Come here for fresh fish and seafood in a pleasant environment with personalized attention. From its varied menu, exquisite dishes like the seafood spaghetti definitely stand out. The seafood-forward menu also features empanadas, chowders, and meats.

El Ancla Restaurant
El Ancla Restaurant

Karai: Located inside the W Hotel Santiago, Karai is an upscale restaurant that serves fascinating Japanese-Peruvian fusion cuisine. If you are craving sushi, this is your spot. Don’t miss out on the fresh ceviche or softshell crab sliders either.

Bocanariz: Chile is one of South America’s largest wine producers. For a crash course in the country’s wine, head to Bocanariz, which showcases over 30 local wines with a food menu built around the wine so that it can be perfectly paired with the country’s best varietals, including chardonnays and cabernet sauvignons.

Bocanariz Restaurant
Bocanariz Restaurant

Borago: Named one of the world’s 50 best restaurants, chef Rodolfo Guzman has been credited with reinventing the Santiago food scene. He is best known for foraging the Chilean landscape, from the mountains to the seas, which results in a unique dining experience.

Where to Stay

Pullman Santiago Vitacura (Ex Atton) Hotel: Located in Santiago’s financial center, near tourist sites and in one of the most sophisticated neighborhoods, Pullman offers spacious rooms with incredible views of the city or Los Leones Golf Club, depending on the direction you are facing.

All Accor

Hotel Boutique Castillo Rojo: What once was a 1920s home is now a boutique hotel with a candy apple red exterior, hence its name, which translates to “red castle.” The old German-mansion-turned-hotel is in the Bellavista neighborhood and features just 19 guest rooms. This artsy option is as unique as the barrio it’s located in.

David Duran is an award-winning travel writer who has visited all seven continents and more than 70 countries. His writing… Read Full Bio
Copenhagen was just named the world’s most livable city. After spending half my year here, I’m not surprised.
Copenhagen

Every few months, I swap Ohio for Copenhagen.

For roughly five or six months of the year, Denmark’s capital becomes home. My boyfriend lives here, which means I’ve had the rare opportunity to experience Copenhagen beyond the typical long weekend itinerary. I’ve settled into routines that make the city feel familiar, from stopping by Netto for groceries to grabbing what I still maintain is the best cinnamon roll I’ve ever had from Lagkagehuset. I’ve spent warm afternoons swimming at Ofelia Plads and Nordhavn, wandered through neighborhoods that rarely make first-time visitor guides, and discovered that some of the city’s best moments happen when there’s no plan at all.

Read more
These 2026 island getaways are surging in popularity right now
Sandals St. Lucia Grande

Expedia just released its latest set of data: The 2026 Island Hot List, a trending list that compiles the emerging islands travelers are searching for before they become the next big thing. According to the newExpedia data, interest in these rising island destinations is up 55% on average year-over-year, while social media mentions have climbed 20% as travelers look for new experiences, better value, and fewer crowds. If you ask me, this is pretty surprising to hear it’s up 55%, especially when I thought islands were already one of the most popular year-round travel destinations.

Ranked #1 on Expedia’s 2026 Island Hot List is St. Lucia, an island I first fell in love with back in 2023 when I went on my honeymoon there. Once you visit here, it’s pretty easy to see why it’s ranked the best for romantic escapes. This destination has been a popular spot for anniversary and honeymoon trips for a long time now — and it doesn’t appear to be slowing down. As travelers move beyond crowded Caribbean hotspots, many are willing to take the extra trek to destinations like St. Lucia for it’s dramatic scenery, romantic resort options like Sugar Beach, and soft adventure focus.

Read more
Six Senses Rome is a peaceful retreat in a beautifully chaotic city
the lobby at Six Senses Rome

Rome is one of the most visited cities in Europe, and by all accounts, it gets crowded. But considering that it’s one of the world’s most important epicenters for history, culture, food and architecture, we can forgive the crowds. After all, complaining about tourism when you’re a tourist is not the way. But booking yourself a peaceful respite to start and end each day most certainly is.

I chose Six Senses Rome as my home base during a recent four-day trip to the city. The property opened in 2023 in the restored 15th-century Palazzo Salviati Cesi Mellini. The historic building sets the tone before you even check in, with restored 600-year-old columns in the main entrance, pale travertine floors, a light-dappled lobby overflowing with greenery, and a massive marble staircase that’s almost comically regal. And its neighbor is the gorgeous San Marcello al Corso Church—so you can start your sightseeing by literally going next door. 

Read more