Skip to main content
  1. Home
  2. Health & Fitness
  3. News

Lacking sleep but maintaining focus? The benefits of creatine go beyond muscle

If you missed precious hours of sleep, studies show supplementing creatine could sharpen your brain and boost sports performance

man working on computer desk
Mizunokozuki / Pexels

Most people have heard of taking creatine to help build muscle. Powerlifters often sing the praises of creatine while lifting, and there’s solid evidence to back it up. Researchers found that supplementing creatine monohydrate while progressive resistance training increases muscle strength in as little as two weeks, while promoting a more significant reduction in body fat percentage compared to just resistance training alone. For some people, it might take a little longer to see results.

In additional studies on the benefits of creatine, researchers are exploring how creatine impacts sleep deprivation and brain performance, highlighting how this popular gym supplement isn’t just useful for swelling those muscles. Let’s check out the research.

The growing research on creatine, sleep, and sports performance

In another small study of elite rugby players, those who were sleep deprived and didn’t take creatine experienced a significant drop in skill performance accuracy on both the dominant and non-dominant passing sides. However, the rugby players who took creatine at 50 or 100 mg/kg didn’t experience this same drop in performance, showing that the creatine helped combat the negative effects on performance from the lack of sleep.

The growing research on creatine, sleep, and brain power

There are multiple examples of studies on creatine and sleep deprivation. For instance, in a study published in the journal Psychopharmacology, the researchers found that after 24 hours of sleep deprivation, supplementing with creatine yielded a positive effect on mood state and tasks that placed a heavy stress on the prefrontal cortex of the brain.

Recommended Videos

In another study published in the journal Scientific Reports, participants were placed in two groups: group one took a high single dose of creatine (0.35g/kg), and group two took a placebo within a 21-hour time period. The participants performed cognitive tests while sleep-deprived at varying timelines following the creatine supplementation.

Results

The researchers concluded that creatine is a suitable supplement for reducing the negative effects of sleep deprivation. The results showed the following:

  • The group that took the high dose of creatine was able to sustain normal levels of ATP and phosphocreatine in the brain even while being sleep deprived.
  • Creatine also prevents a drop in pH level and enhances cognitive performance and processing speed. These benefits continued even after 21 hours of sleep deprivation and were even enhanced beyond a well-rested level in some cases.
  • A high single dose of creatine could partially reverse metabolic alterations and fatigue-related cognitive deterioration.

The takeaway

If you’re facing a cognitively challenging day ahead and you’re working without enough hours of sleep, this research shows that a single high dose of creatine could help boost your cognitive performance and how quickly your brain processes information. 

Steph Green (Steph Zee) is a singer-songwriter and professional writer with over 12 years of experience in healthcare and… Read Full Bio
Topics
The Manual’s Health & Wellness Awards Are Open for Submissions
Clothing, Footwear, Shoe

For years, The Manual has told readers which products actually work. Not which ones arrived in the nicest box, and not which brand bought the most media. Which ones held up after weeks of real use, and were still worth reaching for at the end.

Now we’re bringing that same approach to health. Introducing The Manual Health & Wellness Awards 2026, our first awards program dedicated to the products that help men sleep, train, recover, and feel better. And it’s open to submissions.

Read more
Ditching the boring golf gear: Travis Mathew and Liberty London collaborate to bring personality to the course
Chair, Furniture, Person

I remember watching golf when I was a kid; everyone, and I mean everyone, looked the same. There are rules on a golf course. A collared shirt, no denim, a very specific look is what they go for. It is tradition, and tradition is hard to argue with. Then came Tiger Woods and John Daly. Tiger found a way to make this boring tradition a uniform. You could see the red Nike polo and black pants and knew exactly who it was. Daly? Well, he went the other way and patterns became a wild calling card. Travis Mathew and Liberty London found a way to mix both of these concepts to bring a bold new look to the game of golf.

What makes this collaboration particularly exciting is seeing Liberty’s heritage designs and colour language brought into the world of golf in such a fresh way. The striking print combinations, considered handfeel, and balance of high-performance golfwear with relaxed lifestyle pieces create a collaboration that feels both unexpected and distinctly Liberty. – Pere Bruach, Design Manager at Liberty London

Read more
After 19 Years Away From Basketball, Armando Rodriguez Found His Way Back With Grit, AI, and a Passion That Never Left
Armando Rodriguez basketball player

For basketball enthusiasts, there’s something uniquely inviting and invigorating about the sport. The squeaks as the players move around the shiny court, the whoosh of the spinning ball through the air, and the rush of victory when the basketball glides smoothly through the hoop or bounces off the backboard before the descent. The fast thinking, maneuvers, strategy, and thrill of the game draw people who play for decades.

Sometimes, people are suddenly facing life-changing circumstances that cause them to turn away from the game they love. For skilled basketball player Armando Rodriguez, he stopped playing after a complete T9 spinal cord injury at the young age of 25.

Read more